Percutaneous Absorption

About this book

The microscopic structure of the epidermis and its derivatives; Mathematical models of percutaneous absorption; Mechanism of percutaneous absorption from physicochemical evidence; Cutaneous metabolism of xenobiotics; Occlusion does not uniformly enhance penetration in vivo; Structure activity correlations in percutaneous absorption; Regional variation in percutaneous absorption; Cutaneous permeation of lipophilic molecules, effects of enhancers; Studies on the permeability of infant skin; Interaction of vehicles with model skin membranes in the permeation process; In vivo relationship between percutaneous absorption and transepidermal water loss; Skin contamination and absorption of chemicals from drinking water while bathing or swimming; Classification of percutaneous penetration enhancers, a conceptional diagram; In vivo methods for percutaneous absorption measurements; In vivo animal models for percutaneous absorption; Determination of percutaneous absorption by in vitro techniques; The influence of metabolism on percutaneous absorption; Localization of compounds in different skin layers and its use as an indicator of percutaneous absorption; Evaporation and penetration from sk…